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The results described are not typical and will vary based on a variety of factors.

In the News

New Weight Control Medication: Xenical (Orlistat) & Other News

Hoffmann-Le Roche, Inc., announced recently that the FDA has granted marketing approval of Xinical (Orlistat), a prescription fat enzyme inhibitor which blocks the absorption of dietary fat by approximately 1/3. The product is indicated for weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. When compared to diet alone, weight loss with Xenical also results in measurable improvement in certain obesity-related conditions, such as high blood pressure, high cholesterol and diabetes according to the company.

Unlike other anti-obesity agents that work in the brain to suppress appetite, Xenical through its fat-blocking action works non-systemically in the gastrointestinal tract, not requiring entry into the bloodstream or brain. The product will be available to patients by prescription in the coming weeks.

Xenical is recommended for use three times daily with meals that contain up to 30% fat, consistent with U.S. dietary guidelines. Blocking 1/3 of fat from digestion means that a patient who ingests 60 grams of fat a day may absorb only 40 grams of fat. The other 20 grams will be excreted through the digestive tract.

Xenical is indicated for obese patients with an initial body mass index (BMI) of 30 or more or 27 or more in the presence of other risk factors, such as high blood pressure, high cholesterol or diabetes. Xenical is currently available in 17 other countries; to date, more than 1,000,000 patients have been treated with Xenical.

Gastrointestinal symptoms are the most commonly observed side effects associated with Xenical. These effects are generally mild and transient and may include oily spotting, flatulence with discharge, fecal urgency, fatty or oily stool, oily evacuation increased defecation and fecal incontinence.

There are still no "magic bullets" for weight reduction. Xenical when used in conjunction with a reduced fat diet and a comprehensive weight reduction program in accordance with the Bariatric Physicians Guidelines to include diet & nutrition, exercise, & behavior modification may be a useful tool in the fight against obesity.

Other interesting news in weight control include a study on fidgeting.

Fidgeting may be the way to stay slim. That's the conclusion of a study in which l6 people volunteered to stuff themselves with l,000 extra calories a day for eight weeks. At the end, some had gained as much as l6 pounds, while others had gained as little as 2 pounds. The difference was the "fidget factor."

The study was designed to investigate why some people seem to gain weight while others, eating about the same diet, seem to stay slim. The study was published today in the journal Science.

The result showed that it wasn't the big movements, such as walking or climbing stairs, that made the difference. It was the small, fidgeting-like movements that separated the weight gainers from those who stayed slim.

The people who were burning a lot of extra calories were doing it in the activities of daily life. That could be fidgeting, standing up often, stretching or just the effort to maintain a good posture. Each such muscle movements burns calories and uses some of the excess energy that might otherwise be stored as fat.

Fidgeting, “could explain why some of us escaped gaining weight, whereas others did not, after over-indulging during the past holiday season.”

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